10 Best Audio Interfaces for Guitar and Vocals Together in 2026

Choosing the right audio interface for guitar and vocals together can make the difference between a rough demo and a polished recording. The best options give you clean preamps, enough gain for a vocal mic and instrument input, and low-latency monitoring.

Below, we focus on practical choices for home studios, content creators, and musicians who want one compact interface that can handle both sources with confidence.

Table of Contents

Best 10 Audio Interface for Guitar and Vocals Together Picks for 2026

Studio Upgrade Pick

Focusrite Scarlett 2i2 4th Gen

Focusrite Scarlett 2i2 4th Gen
  • 2 ultra-low-noise mic pres
  • Auto Gain, Clip Safe, and Air mode
  • 24-bit/192kHz recording with software bundle

Best For: Singer-songwriters and home recording

Budget Effects Mixer

Pyle PMUX9 USB Interface

Pyle PMUX9 USB Interface
  • 2 combo inputs plus AUX and RCA
  • 24 preset digital effects
  • 48V phantom power and multiple outputs

Best For: Budget setups needing effects and flexible I/O

Solo Recording Choice

Scarlett Solo 3rd Gen

Scarlett Solo 3rd Gen
  • Mic input plus instrument input
  • Air mode and Gain Halos
  • 24-bit/192kHz with software included

Best For: Solo singer-guitarists needing a compact interface

Versatile Starter Pick

M-AUDIO M-Track Duo

M-AUDIO M-Track Duo
  • Two combo XLR/Line/Instrument inputs
  • USB/direct monitoring for zero latency
  • Crystal Preamps and MPC Beats included

Best For: New users recording vocals and guitar

Budget Starter

M-Track Solo for Guitar and Vocal Recording

M-Track Solo for Guitar and Vocal Recording
  • Combo XLR/line plus instrument input for two-source tracking
  • USB/direct monitoring with headphone and RCA outputs
  • Includes MPC Beats software for quick starts

Best For: Beginners wanting an affordable recording interface

Creator Flex Choice

Hybrid USB Interface with Routing and Auto-Gain

Hybrid USB Interface with Routing and Auto-Gain
  • Dual USB setup works with computer, phone, and iPad
  • 70dB gain plus auto-gain for vocal and guitar capture
  • Loopback and routing tools for streaming and covers

Best For: Creators and musicians who need flexible multi-device recording

Portable 2x2 Recording Interface

Synido USB C Audio Interface for Recording Music

Synido USB C Audio Interface for Recording Music
  • 24-bit/48kHz recording with low-latency design
  • XLR support plus instrument/line switching
  • Three monitoring modes for recording and playback

Best For: Singer-guitarists wanting a compact, easy recording setup

Hybrid Creator Interface

MAONO P2 Dual XLR USB Audio Interface

MAONO P2 Dual XLR USB Audio Interface
  • Dual USB connectivity for computer and mobile workflows
  • 56dB gain with 24-bit/192kHz audio capture
  • Loopback and routing software for streams and covers

Best For: Creators who want hybrid device support and routing tools

Compact Routing Interface

MAONO PS22 Lite USB Audio Interface

MAONO PS22 Lite USB Audio Interface
  • 24-bit/192kHz recording with 56dB preamp gain
  • Dedicated instrument input for guitar
  • Loopback and ProStudio routing software included

Best For: Beginners and home-studio users recording guitar and vocals

Studio Upgrade Pick – Focusrite Scarlett 2i2 4th Gen

If you want an audio interface for guitar and vocals together, the Scarlett 2i2 4th Gen is a strong all-around choice. It gives you two mic pres, two instrument and line inputs, and 24-bit/192kHz recording, so you can track a singer-guitarist setup with room to grow. Features like Auto Gain, Clip Safe, and Air mode make it especially practical for keeping levels under control while adding presence to both voice and guitar.

Best For: Singer-songwriters, home studios, and anyone who wants a polished two-input interface with modern recording aids.

Pros:

  • 2 ultra-low-noise mic preamps support vocals and instruments cleanly
  • Auto Gain and Clip Safe help set levels and avoid clipping
  • Air mode adds vocal and guitar presence in the mix
  • Includes a software bundle with Pro Tools Intro+, Ableton Live Lite, and Cubase LE

Cons:

  • Only 2 inputs, so it is not built for larger multi-source sessions
  • Best suited to USB recording setups rather than mobile standalone use

This is the most refined option here if you care about ease of use and studio-quality sound. It is a straightforward pick when you need one interface to capture guitar and vocals together without a steep learning curve.

Budget Effects Mixer – Pyle PMUX9 USB Interface

The Pyle PMUX9 is a more feature-heavy audio interface for guitar and vocals together if you want built-in effects and lots of routing options. It supports two combo XLR/6.35 inputs plus extra AUX and RCA inputs, and it records at 24-bit/48kHz over USB. The 24 preset digital effects, phantom power, and multiple output choices make it a flexible low-cost option for basic recording and live-style setups.

Best For: Beginners or budget buyers who want onboard effects and flexible input/output connections.

Pros:

  • Two combo inputs support mic and instrument use
  • 24 preset digital effects add reverb, delay, chorus, and more
  • Multiple outputs include phone, stereo, and monitor connections
  • 48V phantom power supports condenser microphones

Cons:

  • Max sample rate is 48kHz, lower than some competing interfaces
  • Windows-focused software compatibility is listed in the notes
  • Feature set is broad, but not as streamlined as simpler recording interfaces

If you want more of a small mixer feel than a pure studio interface, this one stands out. It trades some recording simplicity for extra effects and connectivity, which can be useful for experimenting with vocal and guitar sounds.

Solo Recording Choice – Scarlett Solo 3rd Gen

The Scarlett Solo 3rd Gen is a compact audio interface for guitar and vocals together when you want a simple, reliable recording path. It includes a high-performing mic preamp, an instrument input for guitar or bass, and 24-bit/192kHz conversion for studio-quality capture. Air mode, Gain Halos, and low-noise balanced outputs make it easy to monitor and record with confidence.

Best For: Solo musicians, singer-songwriters, and podcasters who only need one mic and one instrument input.

Pros:

  • Designed for vocals and guitar with a mic input and instrument input
  • Air mode adds clarity to acoustic instruments
  • Gain Halos help prevent clipping during recording
  • Includes starter software like Pro Tools Intro+, Ableton Live Lite, and Cubase LE

Cons:

  • Only one mic channel, so it is best for solo recording rather than duets
  • Fewer input options than larger two-channel interfaces

This is the simplest pick in the group for a singer-guitarist who wants clean results without extra complexity. If your setup is one vocal and one guitar at a time, it covers the essentials very well.

Versatile Starter Pick – M-AUDIO M-Track Duo

The M-AUDIO M-Track Duo is a practical audio interface for guitar and vocals together if you want a straightforward two-input setup. It offers two combo XLR/Line/Instrument inputs with phantom power, 48kHz recording, and USB/direct monitoring for zero-latency playback. The transparent Crystal Preamps and included MPC Beats software make it a solid entry point for recording and streaming.

Best For: New home-recording users who want a simple two-channel interface for vocals and guitar.

Pros:

  • Two combo inputs handle mic, guitar, and line sources
  • USB/direct monitor switch enables zero-latency monitoring
  • Crystal Preamps are designed for clear microphone capture
  • Includes MPC Beats and other software tools

Cons:

  • 48kHz maximum sample rate is lower than higher-end recording interfaces
  • No extra onboard effects are listed in the notes
  • Basic feature set may be limiting for users who want advanced controls

This is a good low-friction choice if you mainly need to plug in a mic and guitar and start recording. It keeps the setup simple while still covering the basics well for practice tracks, demos, and streaming.

Redline Studio Pick – 2×2 24-bit/192kHz Interface for Guitar and Vocals

If you want an audio interface for guitar and vocals together, this 2×2 USB-C model is built for straightforward home recording. Its two combo inputs, Hi-Z support, and 48V phantom power make it easy to plug in a microphone and guitar, while the 24-bit/192kHz converters aim for clean, detailed capture.

Best For: Solo musicians who want a simple, portable interface for recording guitar and vocal takes on Mac, PC, or iOS.

Pros:

  • Two combo jacks support vocals, instruments, and XLR or TRS connections.
  • Hi-Z input and phantom power give flexibility for guitar and condenser mic setups.
  • 24-bit/192kHz recording targets high-fidelity sound with low-noise conversion.
  • Direct monitor feature and 3.5mm headphone jack help with zero-latency tracking.

Cons:

  • Only two channels, so it is geared toward compact setups rather than larger sessions.
  • The feature set is focused on recording basics rather than advanced routing.

This is a practical pick if you want a bus-powered interface that keeps the setup simple and portable. It covers the core needs for laying down guitar and vocals together without extra gear.

Budget Starter – M-Track Solo for Guitar and Vocal Recording

This audio interface for guitar and vocals together keeps things simple for first-time recordists. It gives you one combo XLR/line input with phantom power plus a separate line/instrument input, so you can track a mic and guitar in a compact desktop setup while monitoring through headphones or RCA outputs.

Best For: Beginners who want an affordable, easy-to-use interface for basic guitar-and-vocal recording, streaming, or podcasting.

Pros:

  • One combo XLR/line input and one instrument input cover vocal and guitar duties.
  • Transparent Crystal Preamp is designed to work well with different microphones, including condensers.
  • USB/direct monitoring helps avoid latency during tracking.
  • Includes MPC Beats software plus a software suite to get started quickly.

Cons:

  • 48kHz maximum sample rate is lower than some higher-end interfaces.
  • Single mic combo input means less flexibility than dual-combo alternatives.

For simple recording jobs, this is a no-fuss option that focuses on essentials rather than extras. It suits users who want to plug in, monitor easily, and begin recording guitar and vocals with minimal setup.

Creator Flex Choice – Hybrid USB Interface with Routing and Auto-Gain

For an audio interface for guitar and vocals together, this hybrid USB-C model stands out if you want to move between computer, phone, and iPad recording. It adds 70dB gain, auto-gain, loopback, and routing software, making it a strong fit for creators who record covers, stream, or build multi-app workflows from one desk.

Best For: Creators and musicians who want flexible device connectivity, strong mic gain, and software-based routing for recording and streaming.

Pros:

  • Dual USB ports let you connect a computer and phone or iPad at the same time.
  • 70dB gain and -130dB EIN support low-noise recording with gain-hungry dynamic mics.
  • Auto-gain, mute controls, and direct monitoring simplify live recording and streaming.
  • ProStudio2 routing and loopback help combine guitar, voice, backing tracks, and desktop audio.

Cons:

  • Feature-rich routing may be more than basic users need.
  • Best value depends on whether you actually use the hybrid and software functions.

This is the most workflow-focused option in the group, especially for people who record and stream across multiple devices. If you want one interface that can handle guitar, vocals, and content-creation routing, it offers a lot of flexibility.

Portable 2×2 Recording Interface – Synido USB C Audio Interface for Recording Music

If you want an audio interface for guitar and vocals together, the Synido 2×2 is a simple, portable option for basic home recording, streaming, and quick demos. It offers 24-bit/48kHz recording, a dedicated instrument input, XLR support, and three monitoring modes so you can switch between tracking, mix, and computer playback without much setup.

Best For: Singer-guitarists who want a compact, easy-to-use interface for recording vocals and guitar on a computer or mobile device.

Pros:

  • Supports both XLR microphone input and line/instrument switching for guitar and vocal recording.
  • Three monitoring modes help with recording, live use, and post-production.
  • 48V phantom power adds support for condenser mics.
  • Compact 300g design makes it easy to carry between setups.

Cons:

  • Max sample rate is 48kHz, which is lower than some competing interfaces.
  • ASIO driver download is recommended for best compatibility and performance.

Overall, this Synido model focuses on straightforward operation and portable recording rather than advanced studio routing. It makes sense if you need a practical entry-level audio interface for guitar and vocals together and value ease of use over extra software features.

Hybrid Creator Interface – MAONO P2 Dual XLR USB Audio Interface

The MAONO P2 is built for creators who need an audio interface for guitar and vocals together and want to move easily between computer, phone, and tablet workflows. With dual USB connectivity, 56dB gain, 24-bit/192kHz audio, loopback, and routing software, it suits recording covers, streaming, and mobile music capture without interrupting your setup.

Best For: Guitarists and vocal creators who want hybrid device support plus routing tools for recording and streaming.

Pros:

  • Dual USB ports let you connect to a computer and phone or iPad at the same time.
  • 56dB gain, -130dB EIN, and 24-bit/192kHz recording support clean vocal and guitar capture.
  • Loopback and ProStudio 2 software add flexible routing for covers, streams, and tutorials.
  • Independent mute controls help manage noise during live changes or recording sessions.

Cons:

  • Feature set is more complex than a basic plug-and-play interface.
  • Best value depends on using the routing software and hybrid workflow features.

This is a strong pick if your workflow mixes recording, streaming, and mobile content creation. The MAONO P2 stands out for flexibility, making it especially useful when you want one interface to handle guitar, vocals, and connected-device switching.

Compact Routing Interface – MAONO PS22 Lite USB Audio Interface

If you need an audio interface for guitar and vocals together, the MAONO PS22 Lite keeps the setup simple while still offering useful recording tools. It supports 24-bit/192kHz audio, a dedicated instrument input with impedance adjustment, 56dB preamp gain, and ProStudio routing software, making it a practical choice for home-studio recording and streaming.

Best For: Beginners and home-studio users who want an affordable, compact interface for guitar, vocals, and basic routing.

Pros:

  • Dedicated instrument input is designed for guitar recording.
  • 24-bit/192kHz recording and 56dB preamp support clear vocal capture.
  • ProStudio routing software and loopback expand streaming and DAW flexibility.
  • Plug-and-play design with direct monitoring makes it easy to start.

Cons:

  • Single-device focus means it is less workflow-flexible than hybrid USB models.
  • Its compact, beginner-friendly design may not suit users needing more advanced hardware controls.

The PS22 Lite is a sensible middle ground if you want quality recording features without a bulky interface. It is especially appealing for singer-guitarists who want an easy way to record both parts and still have loopback and routing options available.

How We Picked the Best Audio Interface for Guitar and Vocals Together

We looked for models that are well suited to recording a voice and guitar at the same time, with attention to input flexibility, preamp quality, monitoring options, gain range, and everyday usability. We also favored interfaces that are approachable for first-time buyers but still useful as setups grow.

Quick Comparison: What Matters Most

For an Audio Interface for Guitar and Vocals Together, the main decision points are simple: do you need one mic input and one instrument input, or dual combo inputs for more flexibility? Do you want hardware direct monitoring, loopback for streaming, or software routing? And will your microphone require phantom power?

If you are recording solo voice plus guitar, a 2-in/2-out interface is usually the sweet spot. If you plan to add a second vocalist, stereo sources, or more complex routing, dual XLR or combo inputs are worth the extra headroom.

Key Buying Factors for an Audio Interface for Guitar and Vocals Together

Input Layout

Look for at least one XLR mic input and one instrument or Hi-Z input. Combo inputs are convenient because they can accept either microphones or line-level sources, while dedicated instrument inputs are helpful for direct guitar recording.

Gain and Noise Performance

Vocals and especially dynamic microphones can need substantial clean gain. If you sing quietly or use a less sensitive mic, a model with stronger preamps can reduce the need for extra boosters and help keep noise low.

Monitoring and Latency

Direct monitoring is important when tracking both guitar and vocals, since it lets you hear yourself without distracting delay. For streaming or hybrid recording setups, loopback and routing features can also be valuable.

Phantom Power and Compatibility

If you use a condenser microphone, 48V phantom power is essential. Also confirm your interface works smoothly with your computer or mobile device, especially if you want to record on PC, Mac, iPad, or phone.

Who Should Buy Which Audio Interface for Guitar and Vocals Together?

Beginners who want a straightforward setup should prioritize simple controls, solid gain, and dependable direct monitoring. Singer-songwriters and home recordists may prefer a compact 2-channel unit with combo inputs. Streamers and podcasters who also play guitar should look for loopback, mute, and routing tools. If you want the most flexibility for future expansion, choose a model with stronger gain, dual inputs, and broader software support.

In short, the best Audio Interface for Guitar and Vocals Together is the one that matches your recording style, microphone type, and need for monitoring or streaming features without adding unnecessary complexity.